MyBioSource.com's XRCC1 Antibody (Center) is a Rabbit Polyclonal antibody. This antibody has been shown to work in applications such as: ELISA, Flow Cytometry, Immunofluorescence, Immunohistochemistry, and Western Blot. The XRCC1 Antibody (Center) was generated using RCC, and XRCC1 as the antigen and it reacts with Human.
Description
The protein encoded by this gene is involved in the
efficient repair of DNA single-strand breaks formed by exposure to
ionizing radiation and alkylating agents. This protein interacts
with DNA ligase III, polymerase beta and poly (ADP-ribose)
polymerase to participate in the base excision repair pathway. It
may play a role in DNA processing during meiogenesis and
recombination in germ cells. A rare microsatellite polymorphism in
this gene is associated with cancer in patients of varying
radiosensitivity